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The Adaptor Protein of the Anaphase Promoting Complex Cdh1 Plays An Essential Role in Maintaining Replicative Lifespan and in Learning and Memory

The anaphase promoting complex (APC) or cyclosome is a multi-subunit E3 ubiquitin ligase. Cdc20 [fizzy (fzy), or p55CDC] and Cdh1 [Hct1, srw1, or fizzy-related 1 (fzr1)] encode two adaptor proteins that bring substrates to APC. Both APC-Cdc20 and APC-Cdh1 are implicated in the control of mitosis thr...

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Autors principals: Li, Min, Shin, Yong-Hyun, Hou, Lingfei, Huang, Xingxu, Wei, Zhubo, Klann, Eric, Zhang, Pumin
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914158/
https://ncbi.nlm.nih.gov/pubmed/19160489
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