The PAM-1 aminopeptidase regulates centrosome positioning to ensure anterior-posterior axis specification in one-cell C. elegans embryos

In the one-cell Caenorhabditis elegans embryo, the anterior-posterior (A-P) axis is established when the sperm donated centrosome contacts the posterior cortex. While this contact appears to be essential for axis polarization, little is known about the mechanisms governing centrosome positioning dur...

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Main Authors: Fortin, Samantha M., Marshall, Sara L., Jaeger, Eva C., Greene, Pauline E., Brady, Lauren K., Isaac, R. Elwyn, Schrandt, Jennifer C., Brooks, Darren R., Lyczak, Rebecca
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914133/
https://ncbi.nlm.nih.gov/pubmed/20599902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2010.06.016
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