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Monocyte-Derived Dendritic Cells Exhibit Increased Levels of Lysosomal Proteolysis as Compared to Other Human Dendritic Cell Populations

BACKGROUND: Fine control of lysosomal degradation for limited processing of internalized antigens is a hallmark of professional antigen presenting cells. Previous work in mice has shown that dendritic cells (DCs) contain lysosomes with remarkably low protease content. Combined with the ability to mo...

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Autors principals: McCurley, Nathanael, Mellman, Ira
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914042/
https://ncbi.nlm.nih.gov/pubmed/20689855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011949
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