Invariant Chain Controls H2-M Proteolysis in Mouse Splenocytes and Dendritic Cells

The association of invariant (Ii) chain with major histocompatibility complex (MHC) class II dimers is required for proper antigen presentation to T cells by antigen-presenting cells. Mice lacking Ii chain have severe abnormalities in class II transport, T cell selection, and B cell maturation. We d...

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Bibliografiske detaljer
Main Authors: Pierre, Philippe, Shachar, Idit, Matza, Didi, Gatti, Evelina, Flavell, Richard A., Mellman, Ira
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2000
Fag:
Brief Definitive Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193111/
https://ncbi.nlm.nih.gov/pubmed/10727467
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