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Regulation of apoptosis and priming of neutrophil oxidative burst by diisopropyl fluorophosphate

BACKGROUND: Diisopropyl fluorophosphate (DFP) is a serine protease inhibitor that is widely used as an inhibitor of endogenous proteases in in vitro neutrophil studies. Its effects on neutrophil function are unclear. We sought to determine the biological effects of DFP on human neutrophil apoptosis...

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Bibliographic Details
Main Authors: Tsang, Jennifer LY, Parodo, Jean C, Marshall, John C
Format: Artigo
Language:Inglês
Published: BioMed Central 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913997/
https://ncbi.nlm.nih.gov/pubmed/20609247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-9255-7-32
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