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Adenovirus Expression of IL-1 and NF-κB Inhibitors Does Not Inhibit Acute Adenoviral-Induced Brain Inflammation, but Delays Immune System-Mediated Elimination of Transgene Expression
Despite their ability to provide long-term transgene expression in the central nervous system of naïve hosts, the use of first-generation adenovirus (Ad) vectors for the treatment of chronic neurological disorders is limited by peripheral immunization, which stimulates anti-adenovirus immune respons...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2003
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2913593/ https://ncbi.nlm.nih.gov/pubmed/12946313 |
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