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Blockade of PD-L1 Enhances the Therapeutic Efficacy of Combination Immunotherapy Against Melanoma

Inhibition of anti-tumor T cell responses can be mediated by the productive interaction between the programmed death-1 (PD-1) receptor on T cells and its ligand PD-L1. PD-L1 is highly expressed on both murine bone marrow-derived dendritic cells (DC) and B16 melanoma. In this study, in vitro blockade...

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Bibliografske podrobnosti
Main Authors: Pilon-Thomas, Shari, Mackay, Amy, Vohra, Nasreen, Mulé, James J.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913584/
https://ncbi.nlm.nih.gov/pubmed/20194714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0904114
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