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The tissue-specific expression of TRPML2 (MCOLN-2) gene is influenced by the presence of TRPML1

Mucolipidosis type IV is a lysosomal storage disorder caused by the loss or dysfunction of the mucolipin-1 (TRPML1) protein. It has been suggested that TRPML2 could genetically compensate (i.e., become upregulated) for the loss of TRPML1. We thus investigated this possibility by first studying the e...

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Bibliographische Detailangaben
Hauptverfasser: Samie, Mohammad A., Grimm, Christian, Evans, Jeffrey A., Curcio-Morelli, Cyntia, Heller, Stefan, Slaugenhaupt, Susan A., Cuajungco, Math P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913554/
https://ncbi.nlm.nih.gov/pubmed/19763610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-009-0716-5
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