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A model for testing the immunogenicity of simian immunodeficiency virus (SIV) and simian-human immunodeficiency virus (SHIV) vaccine candidates in mice

HIV-1 Gag protein represents a promising target of cellular immunity-based vaccines due to its immunogenicity and high conservation among diverse viral subtypes. Development of novel and effective Gag-targeted vaccine candidates inducing CD8(+) and CD4(+) T cell responses requires large scale pre-cl...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Xu, Jun, Kelly, Matthew, Denning, Warren, Hel, Zdenek
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913547/
https://ncbi.nlm.nih.gov/pubmed/19428572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jviromet.2009.01.019
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