Association between a 15q25 gene variant, smoking quantity and tobacco-related cancers among 17 000 individuals

Background Genetic variants in 15q25 have been identified as potential risk markers for lung cancer (LC), but controversy exists as to whether this is a direct association, or whether the 15q variant is simply a proxy for increased exposure to tobacco carcinogens. Methods We performed a detailed ana...

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Detalhes bibliográficos
Main Authors: Lips, Esther H, Gaborieau, Valerie, McKay, James D, Chabrier, Amelie, Hung, Rayjean J, Boffetta, Paolo, Hashibe, Mia, Zaridze, David, Szeszenia-Dabrowska, Neonilia, Lissowska, Jolanta, Rudnai, Peter, Fabianova, Eleonora, Mates, Dana, Bencko, Vladimir, Foretova, Lenka, Janout, Vladimir, Field, John K, Liloglou, Triantafillos, Xinarianos, George, McLaughlin, John, Liu, Geoffrey, Skorpen, Frank, Elvestad, Maiken Bratt, Hveem, Kristian, Vatten, Lars, Study, EPIC, Benhamou, Simone, Lagiou, Pagona, Holcátová, Ivana, Merletti, Franco, Kjaerheim, Kristina, Agudo, Antonio, Castellsagué, Xavier, Macfarlane, Tatiana V, Barzan, Luigi, Canova, Cristina, Lowry, Ray, Conway, David I, Znaor, Ariana, Healy, Claire, Curado, Maria Paula, Koifman, Sergio, Eluf-Neto, Jose, Matos, Elena, Menezes, Ana, Fernandez, Leticia, Metspalu, Andres, Heath, Simon, Lathrop, Mark, Brennan, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Genetic Epidemiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913450/
https://ncbi.nlm.nih.gov/pubmed/19776245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ije/dyp288
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