Phase I 3D Conformal Radiation Dose Escalation Study in Newly Diagnosed Glioblastoma: RTOG 9803

PURPOSE: Phase I trial to evaluate the feasibility and toxicity of dose escalated 3DCRT concurrent with chemotherapy in patients with primary supratentorial GBM. MATERIALS/METHODS: 209 patients were enrolled. All received 46 Gy in 2 Gy fractions to PTV(1), defined as GTV plus 1.8 cm. Subsequent boos...

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Autori principali: Tsien, Christina, Moughan, Jennifer, Michalski, Jeff M, Gilbert, Mark R., Purdy, James, Simpson, Joseph, Kresel, John J., Curran, Walter J., Diaz, A., Mehta, Minesh P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913423/
https://ncbi.nlm.nih.gov/pubmed/18723297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2008.05.034
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