OVEREXPRESSION OF ANTIOXIDANT ENZYMES UPREGULATES ARYL HYDROCARBON RECEPTOR EXPRESSION VIA INCREASED SP1 DNA-BINDING ACTIVITY

We previously reported up-regulation of aryl hydrocarbon receptor (AhR) expression as a mechanism by which overexpression of Cu/Zn-superoxide dismutase (SOD) and/or catalase accelerates benzo(a)pyrene (BaP) detoxification in mouse aorta endothelial cells (MAECs). The objective of this study was to i...

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Hauptverfasser: Tang, Tian, Lin, Xinghua, Yang, Hong, Zhou, LiChun, Wang, Zefen, Shan, Guang, Guo, ZhongMao
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913407/
https://ncbi.nlm.nih.gov/pubmed/20478378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2010.05.007
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