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Inhibition of Phosphatidylinositol 3-Kinase Signaling in Hepatic Stellate Cells Blocks the Progression of Hepatic Fibrosis
The hepatic stellate cell (HSC) is the primary cell type in the liver responsible for excess collagen deposition during fibrosis. Following a fibrogenic stimulus, the cell changes from a quiescent vitamin A storing cell to an activated cell type associated with increased extracellular matrix synthes...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2913293/ https://ncbi.nlm.nih.gov/pubmed/19790269 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.23186 |
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