Sodium-Calcium Exchange Is Essential for Effective Triggering of Calcium Release in Mouse Heart

In cardiac myocytes, excitation-contraction coupling depends upon sarcoplasmic reticular Ca(2+) release triggered by Ca(2+) influx through L-type Ca(2+) channels. Although Na(+)-Ca(2+) exchange (NCX) is essential for Ca(2+) extrusion, its participation in the trigger process of excitation-contractio...

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Autors principals: Neco, Patricia, Rose, Beth, Huynh, Nhi, Zhang, Rui, Bridge, John H.B., Philipson, Kenneth D., Goldhaber, Joshua I.
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2010
Matèries:
Cellular Biophysics and Electrophysiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913203/
https://ncbi.nlm.nih.gov/pubmed/20682252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.04.071
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