Targeted overexpression of human α-synuclein in oligodendroglia induces lesions linked to MSA -like progressive autonomic failure

Multiple system atrophy (MSA) is a rare neurodegenerative disease of undetermined cause manifesting with progressive autonomic failure (AF), cerebellar ataxia and parkinsonism due to neuronal loss in multiple brain areas associated with (oligodendro)glial cytoplasmic α-synuclein (αSYN) inclusions (G...

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Autori principali: Stemberger, Sylvia, Poewe, Werner, Wenning, Gregor K., Stefanova, Nadia
Natura: Artigo
Lingua:Inglês
Pubblicazione: Academic Press 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913120/
https://ncbi.nlm.nih.gov/pubmed/20493840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2010.05.008
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