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Insulin Stimulates Human Skeletal Muscle Protein Synthesis via an Indirect Mechanism Involving Endothelial-Dependent Vasodilation and Mammalian Target of Rapamycin Complex 1 Signaling

Objective: Our objective was to determine whether endothelial-dependent vasodilation is an essential mechanism by which insulin stimulates human skeletal muscle protein synthesis and anabolism. Subjects: Subjects were healthy young adults (n = 14) aged 31 ± 2 yr. Design: Subjects were studied at bas...

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Detalhes bibliográficos
Main Authors: Timmerman, Kyle L., Lee, Jessica L., Dreyer, Hans C., Dhanani, Shaheen, Glynn, Erin L., Fry, Christopher S., Drummond, Micah J., Sheffield-Moore, Melinda, Rasmussen, Blake B., Volpi, Elena
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913031/
https://ncbi.nlm.nih.gov/pubmed/20484484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2009-2696
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