Rapamycin administration in humans blocks the contraction-induced increase in skeletal muscle protein synthesis

Muscle protein synthesis and mTORC1 signalling are concurrently stimulated following muscle contraction in humans. In an effort to determine whether mTORC1 signalling is essential for regulating muscle protein synthesis in humans, we treated subjects with a potent mTORC1 inhibitor (rapamycin) prior...

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Main Authors: Drummond, Micah J, Fry, Christopher S, Glynn, Erin L, Dreyer, Hans C, Dhanani, Shaheen, Timmerman, Kyle L, Volpi, Elena, Rasmussen, Blake B
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 2009
Assuntos:
Skeletal Muscle and Exercise
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2678224/
https://ncbi.nlm.nih.gov/pubmed/19188252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2008.163816
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