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Rapamycin administration in humans blocks the contraction-induced increase in skeletal muscle protein synthesis

Muscle protein synthesis and mTORC1 signalling are concurrently stimulated following muscle contraction in humans. In an effort to determine whether mTORC1 signalling is essential for regulating muscle protein synthesis in humans, we treated subjects with a potent mTORC1 inhibitor (rapamycin) prior...

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Main Authors: Drummond, Micah J, Fry, Christopher S, Glynn, Erin L, Dreyer, Hans C, Dhanani, Shaheen, Timmerman, Kyle L, Volpi, Elena, Rasmussen, Blake B
格式: Artigo
語言:Inglês
出版: Blackwell Science Inc 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2678224/
https://ncbi.nlm.nih.gov/pubmed/19188252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2008.163816
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