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Gas-phase rearrangements do not affect site localization reliability in phosphoproteomics data sets

Intramolecular transfer of phosphate during collision-induced dissociation (CID) in ion trap mass spectrometers has recently been described. Because phosphorylation events are assigned to discrete serine, threonine, and tyrosine residues based on the presence of site-determining ions in MS/MS spectr...

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Detalhes bibliográficos
Main Authors: Aguiar, Mike, Haas, Wilhelm, Beausoleil, Sean A., Rush, John, Gygi, Steven P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912977/
https://ncbi.nlm.nih.gov/pubmed/20377248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr1000225
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