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Different integration site structures between L1 protein-mediated retrotransposition in cis and retrotransposition in trans
BACKGROUND: Long interspersed nuclear element-1 (LINE-1 or L1) is a dominant repetitive sequence in the human genome. Besides mediating its own retrotransposition, L1 can mobilize Alu and messenger RNA (mRNA) in trans, and probably also SVA and non-coding RNA. The structures of L1 copies and trans-m...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2010
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2912911/ https://ncbi.nlm.nih.gov/pubmed/20615209 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1759-8753-1-17 |
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