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Prediction of Deleterious Non-Synonymous SNPs Based on Protein Interaction Network and Hybrid Properties

Non-synonymous SNPs (nsSNPs), also known as Single Amino acid Polymorphisms (SAPs) account for the majority of human inherited diseases. It is important to distinguish the deleterious SAPs from neutral ones. Most traditional computational methods to classify SAPs are based on sequential or structura...

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מידע ביבליוגרפי
Main Authors: Huang, Tao, Wang, Ping, Ye, Zhi-Qiang, Xu, Heng, He, Zhisong, Feng, Kai-Yan, Hu, LeLe, Cui, WeiRen, Wang, Kai, Dong, Xiao, Xie, Lu, Kong, Xiangyin, Cai, Yu-Dong, Li, Yixue
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912763/
https://ncbi.nlm.nih.gov/pubmed/20689580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011900
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