Prediction of Deleterious Non-Synonymous SNPs Based on Protein Interaction Network and Hybrid Properties

Non-synonymous SNPs (nsSNPs), also known as Single Amino acid Polymorphisms (SAPs) account for the majority of human inherited diseases. It is important to distinguish the deleterious SAPs from neutral ones. Most traditional computational methods to classify SAPs are based on sequential or structura...

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Bibliografiske detaljer
Main Authors: Huang, Tao, Wang, Ping, Ye, Zhi-Qiang, Xu, Heng, He, Zhisong, Feng, Kai-Yan, Hu, LeLe, Cui, WeiRen, Wang, Kai, Dong, Xiao, Xie, Lu, Kong, Xiangyin, Cai, Yu-Dong, Li, Yixue
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912763/
https://ncbi.nlm.nih.gov/pubmed/20689580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011900
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