Prediction of Deleterious Non-Synonymous SNPs Based on Protein Interaction Network and Hybrid Properties

Non-synonymous SNPs (nsSNPs), also known as Single Amino acid Polymorphisms (SAPs) account for the majority of human inherited diseases. It is important to distinguish the deleterious SAPs from neutral ones. Most traditional computational methods to classify SAPs are based on sequential or structura...

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Detalhes bibliográficos
Main Authors: Huang, Tao, Wang, Ping, Ye, Zhi-Qiang, Xu, Heng, He, Zhisong, Feng, Kai-Yan, Hu, LeLe, Cui, WeiRen, Wang, Kai, Dong, Xiao, Xie, Lu, Kong, Xiangyin, Cai, Yu-Dong, Li, Yixue
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912763/
https://ncbi.nlm.nih.gov/pubmed/20689580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011900
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