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Quantification of Population Structure Using Correlated SNPs by Shrinkage Principal Components

BACKGROUND/AIMS: Association studies using unrelated individuals have become the most popular design for mapping complex traits. One of the major challenges of association mapping is avoiding spurious association due to population stratification. Principal component analysis (PCA) on genome-wide mar...

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Autori principali: Zou, Fei, Lee, Seunggeun, Knowles, Michael R., Wright, Fred A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: S. Karger AG 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912642/
https://ncbi.nlm.nih.gov/pubmed/20413978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000288706
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