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Quantification of Population Structure Using Correlated SNPs by Shrinkage Principal Components
BACKGROUND/AIMS: Association studies using unrelated individuals have become the most popular design for mapping complex traits. One of the major challenges of association mapping is avoiding spurious association due to population stratification. Principal component analysis (PCA) on genome-wide mar...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
S. Karger AG
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2912642/ https://ncbi.nlm.nih.gov/pubmed/20413978 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000288706 |
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