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Synthesis of γ-halogenated ketones via the Ce(IV)-mediated oxidative coupling of cyclobutanols and inorganic halides

A straightforward method for the synthesis of γ-halo-substituted ketones formed via the CAN-initiated oxidative addition of halides to 1-substituted cyclobutanols has been developed. This method has short reaction times, and provides access to a range of bromo and iodo γ-substituted ketones in good...

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Autori principali: Casey, Brian M., Eakin, Cynthia A., Flowers, Robert A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912607/
https://ncbi.nlm.nih.gov/pubmed/20676239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2008.12.114
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