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Polycistronic pre-mRNA processing in vitro: snRNP and pre-mRNA role reversal in trans-splicing

Spliced leader (SL) trans-splicing in Caenorhabditis elegans attaches a 22-nucleotide (nt) exon onto the 5′ end of many mRNAs. A particular class of SL, SL2, splices mRNAs of downstream operon genes. Here we use an embryonic extract-based in vitro splicing system to show that SL2 specificity informa...

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Bibliografische gegevens
Hoofdauteurs: Lasda, Erika L., Allen, Mary Ann, Blumenthal, Thomas
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory Press 2010
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912562/
https://ncbi.nlm.nih.gov/pubmed/20624853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1940010
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