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IQGAP1 is overexpressed in hepatocellular carcinoma and promotes cell proliferation by Akt activation
The scaffold protein IQGAP1 shows elevated levels in several cancer types, but its expression in hepatocellular carcinoma is unknown. We found that 58% of human hepatocellular carcinoma tissue samples had increased IQGAP1 expression compared to adjacent normal tissue. Overexpressing IQGAP1 raised th...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Korean Society for Biochemistry and Molecular Biology
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2912475/ https://ncbi.nlm.nih.gov/pubmed/20530982 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2010.42.7.049 |
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