IQGAP1 is overexpressed in hepatocellular carcinoma and promotes cell proliferation by Akt activation

The scaffold protein IQGAP1 shows elevated levels in several cancer types, but its expression in hepatocellular carcinoma is unknown. We found that 58% of human hepatocellular carcinoma tissue samples had increased IQGAP1 expression compared to adjacent normal tissue. Overexpressing IQGAP1 raised th...

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Bibliografiska uppgifter
Huvudupphovsmän: Chen, Feng, Zhu, Hai-Hong, Zhou, Lin-Fu, Wu, Shan-Shan, Wang, Jing, Chen, Zhi
Materialtyp: Artigo
Språk:Inglês
Publicerad: Korean Society for Biochemistry and Molecular Biology 2010
Ämnen:
Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912475/
https://ncbi.nlm.nih.gov/pubmed/20530982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2010.42.7.049
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