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IQGAP1 is overexpressed in hepatocellular carcinoma and promotes cell proliferation by Akt activation

The scaffold protein IQGAP1 shows elevated levels in several cancer types, but its expression in hepatocellular carcinoma is unknown. We found that 58% of human hepatocellular carcinoma tissue samples had increased IQGAP1 expression compared to adjacent normal tissue. Overexpressing IQGAP1 raised th...

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Detalhes bibliográficos
Main Authors: Chen, Feng, Zhu, Hai-Hong, Zhou, Lin-Fu, Wu, Shan-Shan, Wang, Jing, Chen, Zhi
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society for Biochemistry and Molecular Biology 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912475/
https://ncbi.nlm.nih.gov/pubmed/20530982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2010.42.7.049
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