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IQGAP1 is overexpressed in hepatocellular carcinoma and promotes cell proliferation by Akt activation

The scaffold protein IQGAP1 shows elevated levels in several cancer types, but its expression in hepatocellular carcinoma is unknown. We found that 58% of human hepatocellular carcinoma tissue samples had increased IQGAP1 expression compared to adjacent normal tissue. Overexpressing IQGAP1 raised th...

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Autores principales: Chen, Feng, Zhu, Hai-Hong, Zhou, Lin-Fu, Wu, Shan-Shan, Wang, Jing, Chen, Zhi
Formato: Artigo
Lenguaje:Inglês
Publicado: Korean Society for Biochemistry and Molecular Biology 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912475/
https://ncbi.nlm.nih.gov/pubmed/20530982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2010.42.7.049
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