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IQGAP1 is overexpressed in hepatocellular carcinoma and promotes cell proliferation by Akt activation

The scaffold protein IQGAP1 shows elevated levels in several cancer types, but its expression in hepatocellular carcinoma is unknown. We found that 58% of human hepatocellular carcinoma tissue samples had increased IQGAP1 expression compared to adjacent normal tissue. Overexpressing IQGAP1 raised th...

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Hlavní autoři: Chen, Feng, Zhu, Hai-Hong, Zhou, Lin-Fu, Wu, Shan-Shan, Wang, Jing, Chen, Zhi
Médium: Artigo
Jazyk:Inglês
Vydáno: Korean Society for Biochemistry and Molecular Biology 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912475/
https://ncbi.nlm.nih.gov/pubmed/20530982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2010.42.7.049
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