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Total Synthesis of (±)-Aplykurodinone-1: Traceless Stereochemical Guidance

[Image: see text] The total synthesis of the highly degraded steroidal natural product, aplykurodinone-1 (1), has been accomplished. Key features include a one-flask hydrolysis/retro-aldol/iodolactonization sequence to excise the C(8) hydroxymethylene functionality with retention of stereochemistry,...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Zhang, Yandong, Danishefsky, Samuel J.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2010
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912429/
https://ncbi.nlm.nih.gov/pubmed/20513158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja1035495
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