The Meningococcal Vaccine Candidate Neisserial Surface Protein A (NspA) Binds to Factor H and Enhances Meningococcal Resistance to Complement

Complement forms an important arm of innate immunity against invasive meningococcal infections. Binding of the alternative complement pathway inhibitor factor H (fH) to fH-binding protein (fHbp) is one mechanism meningococci employ to limit complement activation on the bacterial surface. fHbp is a l...

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Autors principals: Lewis, Lisa A., Ngampasutadol, Jutamas, Wallace, Ruth, Reid, Jane E. A., Vogel, Ulrich, Ram, Sanjay
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912398/
https://ncbi.nlm.nih.gov/pubmed/20686663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1001027
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