Murine Gamma-Herpesvirus 68 Hijacks MAVS and IKKβ to Initiate Lytic Replication

Upon viral infection, the mitochondrial antiviral signaling (MAVS)-IKKβ pathway is activated to restrict viral replication. Manipulation of immune signaling events by pathogens has been an outstanding theme of host-pathogen interaction. Here we report that the loss of MAVS or IKKβ impaired the lytic...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Dong, Xiaonan, Feng, Hao, Sun, Qinmiao, Li, Haiyan, Wu, Ting-Ting, Sun, Ren, Tibbetts, Scott A., Chen, Zhijian J., Feng, Pinghui
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912392/
https://ncbi.nlm.nih.gov/pubmed/20686657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1001001
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares