Murine Gamma-Herpesvirus 68 Hijacks MAVS and IKKβ to Initiate Lytic Replication

Upon viral infection, the mitochondrial antiviral signaling (MAVS)-IKKβ pathway is activated to restrict viral replication. Manipulation of immune signaling events by pathogens has been an outstanding theme of host-pathogen interaction. Here we report that the loss of MAVS or IKKβ impaired the lytic...

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Bibliografske podrobnosti
Main Authors: Dong, Xiaonan, Feng, Hao, Sun, Qinmiao, Li, Haiyan, Wu, Ting-Ting, Sun, Ren, Tibbetts, Scott A., Chen, Zhijian J., Feng, Pinghui
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2010
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912392/
https://ncbi.nlm.nih.gov/pubmed/20686657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1001001
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