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Oseltamivir–Resistant Pandemic H1N1/2009 Influenza Virus Possesses Lower Transmissibility and Fitness in Ferrets

The neuraminidase (NA) inhibitor oseltamivir offers an important immediate option for the control of influenza, and its clinical use has increased substantially during the recent H1N1 pandemic. In view of the high prevalence of oseltamivir-resistant seasonal H1N1 influenza viruses in 2007–2008, ther...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Duan, Susu, Boltz, David A., Seiler, Patrick, Li, Jiang, Bragstad, Karoline, Nielsen, Lars P., Webby, Richard J., Webster, Robert G., Govorkova, Elena A.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912389/
https://ncbi.nlm.nih.gov/pubmed/20686654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1001022
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