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Oseltamivir–Resistant Pandemic H1N1/2009 Influenza Virus Possesses Lower Transmissibility and Fitness in Ferrets

The neuraminidase (NA) inhibitor oseltamivir offers an important immediate option for the control of influenza, and its clinical use has increased substantially during the recent H1N1 pandemic. In view of the high prevalence of oseltamivir-resistant seasonal H1N1 influenza viruses in 2007–2008, ther...

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Autors principals: Duan, Susu, Boltz, David A., Seiler, Patrick, Li, Jiang, Bragstad, Karoline, Nielsen, Lars P., Webby, Richard J., Webster, Robert G., Govorkova, Elena A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912389/
https://ncbi.nlm.nih.gov/pubmed/20686654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1001022
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