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Extracellular Matrix, Nuclear and Chromatin Structure, and Gene Expression in Normal Tissues and Malignant Tumors: A Work in Progress

Almost three decades ago, we presented a model where the extracellular matrix (ECM) was postulated to influence gene expression and tissue-specificity through the action of ECM receptors and the cytoskeleton. This hypothesis implied that ECM molecules could signal to the nucleus and that the unit of...

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Detalhes bibliográficos
Main Authors: Spencer, Virginia A., Xu, Ren, Bissell, Mina J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912285/
https://ncbi.nlm.nih.gov/pubmed/17419950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0065-230X(06)97012-2
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