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Targeting surface nucleolin with a multivalent pseudopeptide delays development of spontaneous melanoma in RET transgenic mice
BACKGROUND: The importance of cell-surface nucleolin in cancer biology was recently highlighted by studies showing that ligands of nucleolin play critical role in tumorigenesis and angiogenesis. By using a specific antagonist that binds the C-terminal tail of nucleolin, the HB-19 pseudopeptide, we r...
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Autores principales: | , , , , , , , , , , , |
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Formato: | Artigo |
Lenguaje: | Inglês |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2912263/ https://ncbi.nlm.nih.gov/pubmed/20573279 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-325 |
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