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Seeing red: flushing out instigators of niacin-associated skin toxicity

The use of niacin to improve plasma lipid levels and reduce risk of myocardial infarction is limited by noxious skin effects that result from stimulation of G protein–coupled receptor 109A (GPR109A) in skin immune cells. Niacin causes vasodilation, manifest as rubor (redness) of the head and neck, p...

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Main Authors: Dunbar, Richard L., Gelfand, Joel M.
格式: Artigo
語言:Inglês
出版: American Society for Clinical Investigation 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912206/
https://ncbi.nlm.nih.gov/pubmed/20664168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI44098
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