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PIK3CA and KRAS mutations predict for response to everolimus therapy: now that’s RAD001

Targeted cancer therapeutics can be effective when patients are preselected to maximize the chance of response. Increasingly, molecular markers such as oncogenic DNA mutations are being exploited to help guide patient preselection. These DNA lesions can predict for either a positive or negative resp...

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Dades bibliogràfiques
Autors principals: Mohseni, Morassa, Park, Ben Ho
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912204/
https://ncbi.nlm.nih.gov/pubmed/20664174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI44026
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