Gankyrin plays an essential role in Ras-induced tumorigenesis through regulation of the RhoA/ROCK pathway in mammalian cells

Activating mutations in Ras proteins are present in about 30% of human cancers. Despite tremendous progress in the study of Ras oncogenes, many aspects of the molecular mechanisms underlying Ras-induced tumorigenesis remain unknown. Through proteomics analysis, we previously found that the protein G...

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Detalhes bibliográficos
Main Authors: Man, Jiang-Hong, Liang, Bing, Gu, Yue-Xi, Zhou, Tao, Li, Ai-Ling, Li, Tao, Jin, Bao-Feng, Bai, Bing, Zhang, Hai-Ying, Zhang, Wei-Na, Li, Wei-Hua, Gong, Wei-Li, Li, Hui-Yan, Zhang, Xue-Min
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912196/
https://ncbi.nlm.nih.gov/pubmed/20628200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI42542
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