hNaa10p contributes to tumorigenesis by facilitating DNMT1-mediated tumor suppressor gene silencing

Hypermethylation-mediated tumor suppressor gene silencing plays a crucial role in tumorigenesis. Understanding its underlying mechanism is essential for cancer treatment. Previous studies on human N-α-acetyltransferase 10, NatA catalytic subunit (hNaa10p; also known as human arrest-defective 1 [hARD...

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Detalhes bibliográficos
Main Authors: Lee, Chung-Fan, Ou, Derick S.-C., Lee, Sung-Bau, Chang, Liang-Hao, Lin, Ruo-Kai, Li, Ying-Shiuan, Upadhyay, Anup K., Cheng, Xiaodong, Wang, Yi-Ching, Hsu, Han-Shui, Hsiao, Michael, Wu, Cheng-Wen, Juan, Li-Jung
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912195/
https://ncbi.nlm.nih.gov/pubmed/20592467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI42275
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