Activating transcription factor 4 regulates osteoclast differentiation in mice

Activating transcription factor 4 (ATF4) is a critical transcription factor for osteoblast (OBL) function and bone formation; however, a direct role in osteoclasts (OCLs) has not been established. Here, we targeted expression of ATF4 to the OCL lineage using the Trap promoter or through deletion of...

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Main Authors: Cao, Huiling, Yu, Shibing, Yao, Zhi, Galson, Deborah L., Jiang, Yu, Zhang, Xiaoyan, Fan, Jie, Lu, Binfeng, Guan, Youfei, Luo, Min, Lai, Yumei, Zhu, Yibei, Kurihara, Noriyoshi, Patrene, Kenneth, Roodman, G. David, Xiao, Guozhi
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912190/
https://ncbi.nlm.nih.gov/pubmed/20628199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI42106
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