Treatment with apolipoprotein A-1 mimetic peptide reduces lupus-like manifestations in a murine lupus model of accelerated atherosclerosis

INTRODUCTION: The purpose of this study was to evaluate the effects of L-4F, an apolipoprotein A-1 mimetic peptide, alone or with pravastatin, in apoE(-/-)Fas(-/-)C57BL/6 mice that spontaneously develop immunoglobulin G (IgG) autoantibodies, glomerulonephritis, osteopenia, and atherosclerotic lesion...

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Detalhes bibliográficos
Main Authors: Woo, Jennifer MP, Lin, Zhuofeng, Navab, Mohamad, Van Dyck, Casey, Trejo-Lopez, Yvette, Woo, Krystal MT, Li, Hongyun, Castellani, Lawrence W, Wang, Xuping, Iikuni, Noriko, Rullo, Ornella J, Wu, Hui, La Cava, Antonio, Fogelman, Alan M, Lusis, Aldons J, Tsao, Betty P
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2911877/
https://ncbi.nlm.nih.gov/pubmed/20482780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3020
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