Cell culture and passaging alters gene expression pattern and proliferation rate in rheumatoid arthritis synovial fibroblasts

INTRODUCTION: Rheumatoid arthritis synovial fibroblasts (RASF) are key players in synovial pathophysiology and are therefore examined extensively in various experimental approaches. We evaluated, whether passaging during culture and freezing has effects on gene expression and cell proliferation. MET...

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Bibliografiske detaljer
Main Authors:	Neumann, Elena, Riepl, Birgit, Knedla, Anette, Lefèvre, Stephanie, Tarner, Ingo H, Grifka, Joachim, Steinmeyer, Jurgen, Schölmerich, Jurgen, Gay, Steffen, Müller-Ladner, Ulf
Format:	Artigo
Sprog:	Inglês
Udgivet:	BioMed Central 2010
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2911867/ https://ncbi.nlm.nih.gov/pubmed/20462438 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3010
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Cell culture and passaging alters gene expression pattern and proliferation rate in rheumatoid arthritis synovial fibroblasts

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