The SPRY domain–containing SOCS box protein SPSB2 targets iNOS for proteasomal degradation

Inducible nitric oxide (NO) synthase (iNOS; NOS2) produces NO and related reactive nitrogen species, which are critical effectors of the innate host response and are required for the intracellular killing of pathogens such as Mycobacterium tuberculosis and Leishmania major. We have identified SPRY d...

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Bibliographische Detailangaben
Hauptverfasser: Kuang, Zhihe, Lewis, Rowena S., Curtis, Joan M., Zhan, Yifan, Saunders, Bernadette M., Babon, Jeffrey J., Kolesnik, Tatiana B., Low, Andrew, Masters, Seth L., Willson, Tracy A., Kedzierski, Lukasz, Yao, Shenggen, Handman, Emanuela, Norton, Raymond S., Nicholson, Sandra E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2010
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Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2911665/
https://ncbi.nlm.nih.gov/pubmed/20603330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200912087
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