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A haplotype of CYP2C9 associated with warfarin sensitivity in mechanical heart valve replacement patients

AIMS: The objectives of this study were to determine the distribution of CYP2C9 variants in Koreans and investigate their association with warfarin dose requirements in patients who received MHVRs. METHODS: All nine exons, intron–exon junction, and promoter region of CYP2C9 were amplified and direct...

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Detalhes bibliográficos
Main Authors: Lee, Su-Jun, Jang, Yin Jin, Cha, Eun-Young, Kim, Ho-Sook, Lee, Sang Seop, Shin, Jae-Gook
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2911551/
https://ncbi.nlm.nih.gov/pubmed/20653674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2010.03688.x
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