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EGFR/Met association regulates EGFR TKI resistance in breast cancer
Breast cancers show a lack of response to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs), despite 30% of tumors expressing EGFR. The mechanism of this resistance is unknown; however, we have recently shown that Met kinase activity compensates for loss of EGFR kinase activi...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
BioMed Central
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2911419/ https://ncbi.nlm.nih.gov/pubmed/20624308 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-2187-5-8 |
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