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The Number of Vitamin D Receptor Binding Sites Defines the Different Vitamin D Responsiveness of the CYP24 Gene in Malignant and Normal Mammary Cells

Primary 1α,25-dihydroxyvitamin D(3) (1α,25(OH)(2)D(3))-responding genes are controlled by the vitamin D receptor (VDR) binding to specific sites (VDREs) that are located within the regulatory regions of these genes. According to previous studies, the gene encoding 25-dihydroxyvitamin D(3) 24-hydroxy...

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Hlavní autoři: Matilainen, Juha M., Malinen, Marjo, Turunen, Mikko M., Carlberg, Carsten, Väisänen, Sami
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2911343/
https://ncbi.nlm.nih.gov/pubmed/20460683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.124073
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