טוען...
Serine Residues in the Cytosolic Tail of the T-cell Antigen Receptor α-Chain Mediate Ubiquitination and Endoplasmic Reticulum-associated Degradation of the Unassembled Protein
The T-cell antigen receptor (TCR) α-chain (TCRα) is a type I integral membrane protein that becomes ubiquitinated and targeted to the endoplasmic reticulum (ER)-associated degradation (ERAD) pathway when it fails to assemble into the heteromeric TCR complex. Remarkably, TCRα has a cytosolic tail of...
שמור ב:
Main Authors: | , , |
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פורמט: | Artigo |
שפה: | Inglês |
יצא לאור: |
American Society for Biochemistry and Molecular Biology
2010
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נושאים: | |
גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2911338/ https://ncbi.nlm.nih.gov/pubmed/20519503 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.127936 |
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