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Deletion of Switch 3 Results in an Archaeal RNA Polymerase That Is Defective in Transcript Elongation
Switch 3 is a polypeptide loop conserved in all multisubunit DNA-dependent RNA polymerases (RNAPs) that extends into the main cleft of the RNAP and contacts each base in a nascent transcript as that base is released from the internal DNA-RNA hybrid. Plasmids have been constructed and transformed int...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2911337/ https://ncbi.nlm.nih.gov/pubmed/20511223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.094565 |
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