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Glutathione Synthesis and Turnover in the Human Erythrocyte: ALIGNMENT OF A MODEL BASED ON DETAILED ENZYME KINETICS WITH EXPERIMENTAL DATA

The erythrocyte is exposed to reactive oxygen species in the circulation and also to those produced by autoxidation of hemoglobin. Consequently, erythrocytes depend on protection by the antioxidant glutathione. Mathematical models based on realistic kinetic data have provided valuable insights into...

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Main Authors: Raftos, Julia E., Whillier, Stephney, Kuchel, Philip W.
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2911318/
https://ncbi.nlm.nih.gov/pubmed/20498365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.067017
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