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Glutathione Synthesis in Human Erythrocytes: II. PURIFICATION AND PROPERTIES OF THE ENZYMES OF GLUTATHIONE BIOSYNTHESIS

The two enzymes required to synthesize glutathione de novo have been purified from human erythrocytes. Glutamylcysteine synthetase was purified 4300-fold and was approximately 80% pure based on polyacrylamide gel electrophoresis. The purified enzyme catalyzes the formation of 30.5 μmoles of γ-glutam...

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Auteurs principaux: Majerus, Philip W., Brauner, M. J., Smith, M. B., Minnich, Virginia
Format: Artigo
Langue:Inglês
Publié: 1971
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC442063/
https://ncbi.nlm.nih.gov/pubmed/5097571
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